
June 7, 2024
Aveiro, Portugal
Program
Registration and Welcome
08:30 - 10:00 Registration
09:00 - 09:10 Welcome message by the Director of the Institute of Biomedicine and of the Dep. of Medical Sciences, University of Aveiro
09:10 -09:20 Opening of the symposium by the organizers
9:20 - 10:45 Lipids as mediators and biomarkers in immunity and infection
Chairs: Bruno Neves and Catarina Almeida, University of Aveiro
9:20 - 10:00 Dániel Torocsik. Hungarian Research Network (HUN-REN) “Sebaceous glands of the skin - at the crossroads of lipid metabolism and inflammation”
10:00 - 10:20 Ricardo Jorge Leal Silvestre. University of Minho, Portugal “Intramacrophage lipid accumulation and susceptibility to Leishmania infection”
10:20 - 10:30 Q&A
10:30 - 10:35 Flash-talk 1: Marta Fernandes, IMM-João Lobo Antunes, Portugal. "Sphingosine kinase activity is essential for IL-7R-mediated signaling in acute lymphoblastic leukemia, but not in healthy lymphocytes"
10:35 - 10:40 Flash-talk 2: Catarina Andrade. I3S, Portugal. "Examining how Enzyme Replacement Therapy affects the invariant Natural Killer T cells in individuals with Acid Sphingomyelinase Disease"
10:40 - 10:45 Q&A
10:45 - 11:15 Coffee Break / Poster Session.
10:15 - 12:50 Lipid signaling in tissue regeneration and aging
Chairs: Sandrina Nóbrega Pereira e Bruno Neves, University of Aveiro
10:15 - 11:55 Nektarios Tavernarakis. University of Crete, Greece
"Nuclear lipid droplet deposition during ageing"
11:55 - 12:15 Maria João Sarmento. IMM-João Lobo Antunes, Portugal “How the nuclear envelope grows old: the role of ether lipids in healthy human aging”
12:15 - 12:25 Q&A
12:25 - 12:35 Daniela Bispo. CICECO - University of Aveiro, Portugal “Understanding Mesenchymal Stem Cell Osteogenesis Variability among Donors: a Step Forward with NMR Lipidomics”
12:35 - 12:40 Flash-talk 3: Júlia Silva, iBiMED, University of Aveiro, Portugal "The impact of systemic lipids on the reprogramming of mouse fibroblasts into induced pluripotent stem cells"
12:40 - 12:50 Q&A
12:50 - 14:15 Lunch* / Poster Session
*Lunch is not provided for the participants.
14:15 - 15:50 Lipid remodeling in cancer
Chairs: Luisa Helguero and Rita Ferreira, University of Aveiro
14:15 - 14:55 Tony Petan. Jožef Stefan Institute, Slovenia “From Fat to Signals of Life & Death: Lipid Droplets Control the Generation of Mitogenic Lipid Mediators and Ferroptotic Death Signals”
14:55 - 15:15 Ana Maria Gil. CICECO - University of Aveiro, Portugal “Nuclear Magnetic Resonance (NMR) lipidomics – an holistic insight into cancer cell metabolism”
15:15 - 15:25 Q&A
15:25 - 15:35 Ana Luisa Ferro Magalhães. IMM-João Lobo Antunes, Portugal “A positive feedback loop between IFN-γ signaling and cholesterol uptake sustains PD-L1 expression in breast cancer cells”
15:35 - 15:40 Flash-talk 4: Diogo Estêvão, i3S and ICBAS, Portugal. "Metabolic deregulation: how rectal cancer cells escape radiotherapy-induced cell death"
15:40 - 15:50 Q&A
15:50 - 16:10 Coffee Break / Poster Session
16:10 - 16:40 Round Table: Lipid Biomarkers and Therapeutic Targets
Chair: Francisco Amado, Dep. Medical Sciences, University of Aveiro
Dániel Torocsik, MD, PhD. Hungarian Research Network (HUN-REN).
Alex Dickens, PhD. Turku Bioscience Centre, University of Turku, Finland
Maria Luísa Dória, PhD. R&D Department, Bial, Portugal
Christian Neves, MD. CHBV, Aveiro and iCBR- University of Coimbra, Portugal
16:40 - 16:50 Best Flash talk and Best poster award Sponsored by Lipotype
16:50 - 17:00 Closing remarks